K-R01 Transition to Independence Program

The K-R01 Transition to Independence Program is available to Assistant Professors (in rank ≤ 7 years) and early Associate Professors (in rank ≤ 4 years) conducting clinical or translational research and aims to place investigators further on the path to be competitive for R01 awards.

    Nature and purpose

    CTSI will provide funds, specialized career development, and dedicated support of senior investigators for K awardees interested in clinical and translational research. The K-R01 Transition to Independence Program is designed to support faculty by providing mentorship, oversight, programming and pilot funds.

    This two-year program aims to place junior investigators, who have K awards, further on the path to be competitive for R01 awards. This RFA will be issued annually. Success of this program will be judged by the number of awardees who move forward to secure NIH R01 grants, and R01 equivalent funding for clinical and translational research.

    Applications from underrepresented populations are strongly encouraged.

    Current Scholars

    Current Scholars

    Antonella Borgatti, DVM, MS, Dipl. ACVIM, Dipl. ECVIM-CA

    College of Veterinary Medicine
    Mentors: Bruce Walcheck, Jaime F. Modiano, Joseph S. Koopmeiners
    Project Title: Utilizing antibody-dependent cell-mediated cytotoxicity by natural killer cells as a treatment strategy for canine B-cell malignancies

    Jazmin Camchong, PhD

    Department of Psychiatry and Behavioral Sciences
    Mentors: Kelvin Lim, Mark Fiecas
    Project Title: Longitudinal trajectory of neuromodulation and cognitive training effects in alcohol use disorder

    Jose Debes, MD, MS

    Department of Medicine
    Mentors: David Boulware, Joseph Koopmeiners
    Project Title: Detection of viral hepatitis-related liver cancer by immune profiling

    Sarah Hoffman, PhD, MPH, MSN, RN

    School of Nursing
    Mentors: Jayne Fulkerson, John Connett, Abigail Gewirtz
    Project title: A family mindfulness intervention for war-affected families: Feasibility of a CBPR approach and the contextual adaptation of an evidence-based intervention addressing intergenerational trauma

    Casey P. Johnson, PhD

    Department of Veterinary Clinical Sciences
    Mentors: Cathy S. Carlson, Baolin Wu, Gregory Metzger
    Project title: Advanced quantitative MRI methods for early detection and monitoring of avascular necrosis of the femoral head

    Amanda Klein, MS, PhD

    Department of Pharmacy Practice and Pharmaceutical Sciences, Duluth
    Mentors: Donald Simone, Carolyn Fairbanks, John Connett
    Project Title: KATP channel prodrugs as therapeutics for chronic pain and substance abuse disorders

    Katie Loth, PhD, MPH

    Department of Family Medicine and Community Health
    Mentors: Jerica Berge, Jayne Fulkerson, James S. Hodges
    Project Title: Exploring the momentary mechanisms of a broad range of food-related parenting practices among racially/ethnically and socioeconomically diverse parent-child dyads.

    Melanie Nicol, PharmD, PhD

    Department of Experimental and Clinical Pharmacology
    Mentors: Paul R. Bohjanen, James S. Hodges
    Project Title: The role of inflammation in antiretroviral concentrations in genital and central nervous system compartments

    Alexa Pragman, MD, PhD

    Department of Medicine
    Mentors: Chris Wendt, Cavan Reilly
    Project Title: Chronic respiratory symptoms and microbiota alterations following high-risk exposures

    Elizabeth Rogers, MD, MAS

    Department of Medicine and Pediatrics
    Mentors: Anne Joseph, John Connett, David Eton
    Project Title: Treatment burden, engagement in care, and glycemic control in low-income patients with diabetes

    Chetan Shenoy, MBBS, MS

    Department of Medicine
    Mentors: Russell Luepker, John Connett
    Project Title: Integrative phenotyping for risk stratification in cardiac sarcoidosis

    Ferenc Toth, DVM, PhD, DACVS

    College of Veterinary Medicine
    Mentors: Cathy Carlson, Aaron Rendahl, Brenda Ogle
    Project Title: Facilitated repair of focal cartilage defects using 3d bioprinted scaffolds seeded with human induced pluripotent stem cell-derived chondrocytes

    Beshay Zordoky, MSc, PhD

    Department of Experimental and Clinical Pharmacology
    Mentors: Pamala Jacobson, Alessandro Bartolomucci, Kendall Wallace, Esam El Fakahany, Haitao Chu
    Project Title: Hypertension exacerbates doxorubicin-induced vascular aging

    Former Scholars

    Former Scholars

    Jason Baker, MD, MS

    Primary mentor: James Neaton, PhD
    Project title: The coagulopathy of HIV infection 

    Melena Bellin, MD

    Primary mentor: Antoinette Moran
    Additional mentor: James Hodges
    Project title: Assessing beta cell loss and islet engraftment after islet autotransplantation

    Maneesh Bhargava, MD

    Primary mentor: Christine Wendt
    Additional mentor: Baolin Wu
    Project title: Biomarkers to predict outcomes in acute respiratory distress syndrome

    Cari Clark, ScD

    Primary mentor: Mary Jo Kreitzer
    Additional mentor: John Connett
    Project title: Impact of yoga on violence survivor's mental and cardio metabolic health: A feasibility study of a cluster randomized trial 

    Kathryn Cullen, MD

    Primary mentor: Kelvin O. Lim
    Additional mentor: Lynn Eberly
    Project title: Intravenous ketamine in adolescent treatment-resistant depression: Efficacy and brain mechanisms

    Paul Drawz, MD

    Primary mentor: Hassan Ibrahim
    Additional mentor: Kyle Rudser
    Project title: Treatment of masked hypertension 

    Allyson Hart, MD, MS

    Mentors: Ajay Israni, John Connett
    Project title: Decision support needs for african american kidney transplant candidates

    Theresa Laguna, MD, MSCS

    Primary mentor: Christine Wendt
    Additional mentor: Cavan Reilly
    Project title: Biomarkers of injury and destruction in the cystic fibrosis lung 

    Julie Ostrander, PhD

    Primary mentor: Douglas Yee
    Additional mentor: Chap Le
    Project title: PELP1 localization as a biomarker for early mammary carcinogenesis and response to chemoprevention

    Lynda Polgreen, MD, MS

    Primary mentor: Chester Whitley
    Additional mentor: William Thomas
    Project title: Cross-sectional study of associations of osteocalcin with obesity, insulin resistance, adipokines and inflammation in the mucopolysaccharidoses 

    Zohar Sachs, MD, PhD

    Mentors: David Largaespada, Karen Sachs
    Project title: Immunoproteasome inhibition to target AML stem cells

    Karina Quevedo, PhD

    Primary mentors: Kamil Ugurbil and Kathleen Thomas
    Co-mentors: John Strupp and Susan Wei
    Project title: How to train your brain: Neurofeedback and changing brain activity in adolescent depression

    Kristine Talley, PhD, RN, GNP-BC

    Primary mentor: Jean F. Wyman
    Additional mentor: James Neaton
    Project title: Preventing toileting disability in frail older women

    Deanna Teoh, MD

    Mentors: Shalini Kulasingam, Rachel Isaksson Vogel
    Project title: Optimizing harms and benefits of cervical cancer screening for HPV-vaccinated women: Screening test performance and acceptability of reduced screening


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