ODAT Translational Research Funding

 Patient with Injury Walks on Treadmill Wearing Advanced Robotic Exoskeleton Legs

Turn your innovation into a product, service or approach that improves human health with support from CTSI’s Office of Discovery and Translation (ODAT).

Funding areas of interest

Funding is not limited to innovations in the above-listed areas of interest. Areas of interest are subject to change with emerging health needs, such as COVID-19.

Apply for funding

Applications are accepted throughout the year, following a structured review and decision-making process. See the review schedule by clicking the "Apply now" button below. 

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How we support our grantees


Since 2012, ODAT has awarded more than $19 million in ODAT Translational Funding to support University innovators developing novel solutions for unmet human health needs.

Guidance from experts

ODAT draws from its broad network of University- and industry-based experts to offer guidance to awardees. Advisory support is tailored to each innovation to address potential development barriers and create a feasible pathway to impact.

Collaborative project management

Our team understands what it takes to move human health innovations from idea to impact. With considerable experience in both academia and medical industries, the ODAT team works collaboratively with awardees and experts to guide projects and support successful outcomes. 




Maurice Hicks Jr. and David Nguyen, PhD. Vertex 360 Platform Prototype Development and Pilot

Syed Peer, MD. Design and Development of Automated Chest Compression Device for Pediatric Cardiopulmonary Resuscitation


Barham Abu Dayyeh, MD, MPH (Mayo Clinic). Vacuum Assisted Electroporation to Treat Anastomotic Leaks

Kate Adamala. Trumpet biocomputing diagnostics platform

Waleed Brinjikji, MD (Mayo Clinic). Lumbo-venous CSF Shunt for Treatment of Communicating Hydrocephalus

Terence Burns, MD, PhD (Mayo Clinic). A first-in-human microperfusion system for in situ CNS discoveries

Mohamad Bydon, MD (Mayo Clinic). Development of a Semi-Automated Intraoperative Rod Bending Machine

Monika Chauhan, PhD. Generation and characterization of a mini-promoter for DNA repair disorders

Sarah Espinoza, PhD. Move and Thrive: Addressing Teen Health Inequities through a Physical Activity Online Platform

Gwenyth Fischer, MD and Ahmed Selim, MD (Fort Worth Heart). Targeted Cardio-Cerebral ECMO (TC-ECMO)

Gwenyth Fischer, MD. Embryo Transfer System

Ognjen Gajic, MD (Mayo Clinic). Reliable Assessment of Rare but life-thrEatening Atypical Infections (RARE-AI)

Hao Gong, PhD (Mayo Clinic). Enhanced assessment of bone marrow pathology using a deep-learning-based virtual non-calcium technique in multi-energy computed tomography

Thorston Gruenheid, DDS, PhD, MHA. Digital workflow for the fabrication of nasoalveolar molding devices for the treatment of infants with cleft lip and palate

Vadim Gurvich, PhD, MBA. Development of Novel Drugs to Promote Epithelial Healing

Jiarong Hong, PhD. Real-time Peritonitis Detection for Pediatric PD using Deep Learning Digital Inline Holography

Narayan (Guru) Kowlgi, MBBS (Mayo Clinic) and Samuel Asirvatham, MD (Mayo Clinic). Artificial Intelligence to Detect Sites of Autonomic Cardiac Innervation to Guide Ablation of Arrhythmias

Sandy Liu, MD. Smartphone based urinalysis test kit for early screening of diabetes and chronic kidney disease

Branden Moriarity, PhD and Beau Webber, PhD. Engineered Memory T cells as a Platform to Treat Enzymopathies

Jonathan Morrison, MB, ChB, PhD (Mayo Clinic). Vascular Isolation and Perfusion for Ischemic Rescue (VIPER)

Rahel Nardos, MD, MCR, FPMRS. Surgical Tool Innovation for Pelvic Organ Prolapse

Jacob Orme, MD, PhD (Mayo Clinic). ADAMs Inhibition to Overcome Prostate Cancer Stockholm Syndrome

Paul Robbins, PhD. Pharmacokinetic analysis of novel senolytics

Nishant Saran, MBBS (Mayo Clinic). Mechanical Percutaneous Septal Myectomy Device

Mauro Schenone, MD (Mayo Clinic). Fetal Ex-Utero Support System (FESS)

Jonathan Strutt, MD. Nasogastric tube confirmation with pH device in neonates

Alena Talkachova, PhD. Prediction of AF ablation outcomes based on intrinsic complexity of ECG signal

Efrain Torres and Michael Garwood, PhD. Towards the development of a compact, silent, and affordable pediatric MRI system

George Vasmatzis, PhD (Mayo Clinic). Detection of high-copy number tumor-specific chromosomal rearrangements in circulating-free DNA from the plasma of high-grade glioma patients

Jian-Ping Wang, PhD. Magnetic Particle Spectroscopy


Mohamad Alkhouli, MD. Cryo-Facilitated method for transcatheter removal of tissue and foreign materials

Shai Ashkenasi, PhD. Assessing cancer metastases in cervical lymph nodes by photoacoustic lifetime imaging

Samira Azarin, PhD. In vivo validation of biomaterial technology for treatment of metastatic ovarian cancer

Roy Cho, MD. Breath sensing lung cancer detection 

Beth Groenke, DDS, and John Sartori, PhD. PhysiAroma - harnessing olfaction to manage chronic pain

Julia Heneghan, MD. A novel tool to assess outcomes after critical illness in children with complex medical needs

Marc Hillmyer, PhD, and Robroy MacIver, MD (Children's MN). Tracheal stents for bronchomalacia in the pediatric population

Erik Jensen, MD. Dissolvable stent for sutureless pancreatic surgery

Harmeet Malhi, MBBS (Mayo Clinic) and William Pomerantz, PhD (UMN). Epigenetic inhibitors for the treatment of alcoholic hepatitis

Timothy O'Brien. iPSC derived cartilage cells for treatment of osteoarthritis

Mukesh Pandey, PhD (Mayo Clinic). cGMP synthesis of [68Ga]Ga-Bisphosphate for PET imaging of bacterial infection over inflammation in osteomyelitis foreign body rat model

William Pomerantz, PhD. BPTF degradation as a new epigenetic therapy approach for pediatric cancers

Elizabeth Rajan. Flexible tube-assist balloon dilator with camera: Self-dilation of benign esophageal strictures 

John Sperling, MD (Mayo Clinic) and Scott Riester, MD (Mayo Clinic). Rotator cuff regeneration using BMP5

Jonathan Strutt, MD. Capillary refill time measurement utilizing mobile application (Cap App) in children

Emanuel Trabuco, MD (Mayo Clinic). Purified exosome product/urethral delivery device as a novel platform to treat stress urinary incontinence

Chun Wang, PhD. Insulin stabilization: in vitro proof-of-concept

Alik Widge, PhD. Market research for network neurotherapeutics

Natasha Wright, PhD. Rapid, on-demand peritoneal dialysis fluid compounding for low resource settings

Longjun Wu, PhD (Mayo Clinic). Targeting TREM2 for the treatment of amyotrophic lateral sclerosis


Taymy Caso, PhD, and G. Nic Rider, PhD, LP. Gender Journey: exploring gender identity and healthy development using a web-based application.

Andrew Hansen, PhD. Pediatric mobile standing wheelchair for children with disabilities

David Haynes, PhD and Pinar Karaca-Mandic, PhD. Smart Community Health

Linda Koehler, MD. Novel Portable Device for the Treatment of Lymphedema

Bryan Ladd, MD. Fascial Closure Device

Hubert Lim, PhD. Enhancing Hearing Using Noninvasive Bimodal Neuromodulation with Novel "Ampear Buds" Technology

Anne Chevalier McKechnie, PhD, RN. Improving inclusivity of content, delivery, and testing of the Preparing Heart and Mind (TM) care program designed for families of infants prenatally diagnosed with complex congenital heart disease. *Jointly supported with ODAT Translational Program

Kathleen, Miller, MD. Move and Thrive: addressing teen health inequities through a physical activity online platform.

Nissrine Nakib, MD, and Dwight Nelson, PhD. Clinical Prototype Build: Bladder Activity Targeting Tool

Timothy O'Brien, DVM, PhD. iPSC Derived Cartilage Cells for Treatment of Osteoarthritis

Paul Orchard, MD and Damien Fair, PhD. Development of a novel, computerized scoring system for cerebral adrenoleukodystrophy.

Mukesh Pandey, PhDAditya Bansal, PhDSean Park, MD, PhD, and Haidong Dong, MD, PhD (Mayo Clinic). Design, Synthesis and Preliminary Evaluation of B-11 Antibody Fragments for PD-L1 PET Imaging

Rita Perlingeiro, PhD. Delivery Optimization of MayoPaxon in Non-human Primates

Paolo Pianosi, MDRajesh Rajamani, PhD. Ambulatory Breathing Sensor To Analyze Ventilatory Pump Function

Elizabeth Rajan, MD (Mayo Clinic). Flexible Tube-assist Balloon Dilator with Camera: Self-dilation of Benign Esophageal Strictures

Kyriakie M. Sarafoglou, MD. Drug-delivery mechanism to increase adherence in patients with adrenal insufficiency

Wendy St. Peter, PharmD. Reduce medication-related disparities in African American patients with chronic kidney disease

Christopher Tignanelli, MD (UMN), Rachel Morris, MD (Medical College of Wisconsin). An Innovative eHealth Platform to Facilitate Shared Decision-Making for Older Adult Trauma Patients

Lynda Welage, PharmD and Randall Seifert, PharmD. Rural medication access


Conrado Aparicio, PhD. Easy wearable devices based on cationic biopolymer membranes for point-of-care collecting/self-sampling high loads of viral particles

Alessandro Bartolomucci, PhD. A new class of C3aR1 agonists for the treatment of obesity

Jan Czyzyk, MD. Development of a novel antibody to serpinB13 for therapy in diabetes

Arthur Erdman, PhD, and Andrew Grande, MD. A novel steerable microcatheter to Improve COVID19 stroke outcomes

Rumi Faizer, MD and Victor Barocas, PhD . A Compliant Stent-graft to Lower Blood Pressure in Patients with Aortic Disease.

Linsey Griffin, PhD, and William Durfee, PhD. MNmask: University of Minnesota's novel method for N95 alternatives

Daniel Harki, PhD. Development of Selective Aurora Kinase A Degraders for the Treatment of N-Myc-driven Cancers

Chris Hogan MD. A high flow hood to mitigate droplet and aerosol transmission

Robert Schumacher, PhDDavid Ingbar, MDTimothy Rich, MD. Development of a T3 formulation for patients with COVID-19-induced ARDS

Man Liu, PhD. Treatment of cardiac diastolic dysfunction with a mitoTEMPO analog

Venkatram Mereddy, PhD. Novel Drugs Targeting Metabolic Plasticity for Breast Cancer Treatment

Li Ou, PhD and Chester Whitley, MD, PhD. A novel gene editing platform to treat Tay-Sachs and Sandhoff diseases

Michael Pitt, MD, and John Sartori, PhD. Q-Rounds: taking the waiting around out of rounds with a virtual queue

William Pomerantz, PhD. Development of a Selective BRD4 inhibitor as an Epigenetic Anti-Cancer Therapeutic

Luis Savastano, MD, PhD (Mayo Clinic). Minimally Invasive Drainage of Subdural Hematomas

Subbaya Subramanian, PhD. Engineered Exosomes for the Treatment of Advanced Stage Colorectal Cancer

Richard Vile, PhD (Mayo Clinic) and Ruben Harris, PhD. Translation of an APOBEC3B-modified vaccine, in combination with checkpoint inhibition, for the treatment of adult human, and companion animal canine, glioblastoma

Natasha Wright, PhDMichelle Rheault, MDIbrahim Yekinni, MBBS. Rapid, on-demand peritoneal dialysis fluid compounding for low resource settings

Collaboration with Earl E. Bakken Medical Devices Center Innovation Fellows Program. Project: Device for neonatal cord management to support kangaroo care


Andres Acosta, MD, PhD (Mayo Clinic). Development of Selective Ileo-Colonic Bitter Taste 2 Receptor 5 Agonist for Treatment of Obesity and Type 2 Diabetes

Mahmoud Al-Kofahi, PhD and Kyriakie M. Sarafoglou, MD. drug-delivery mechanism to increase adherence in patients with adrenal insufficiency

Sandra Armstrong, PhD. Developing improved pertussis vaccines

Michael Barry, PhD (Mayo Clinic), and Alexander Khoruts, MD. Vaccines to Combat Clostridioides (Clostridium) Difficile

Samuel Cramer, MDIn collaboration with Cerovations, LLC. Instrumented External Ventricular Drain

Sarah Elfering, MD, Priya Verghese, MD, MPH, and Ibrahim Yekinni, MBBS. Reducing infection risks in pediatric patients on peritoneal dialysis

Arthur Erdman, PhDAhmed Selim, MD. Translational Development of a Targeted Cardiocerebral Extracorporeal Membrane Oxygenation (TC-ECMO) System

James M. Ervasti, PhD, and David D. Thomas, PhD, and Joseph M. Muretta, PhD. Mini-/Micro-Dystrophin Actin Binding Domain 1 Gain-of-Affinity

John Ferguson, PhDAdriana Seelye, PhDTonya Rich, PhD, OT; Logan Cates, MA CCC-SLP; Don MacLennan, MA, CCC, UMN and Minneapolis VA Health Care System. Just One Thing: Custom Care Plans for Caregivers

Gary Goldish, MD. Caregiver Assistive Wheelchair Control

Alan Marmorstein, PhD (Mayo Clinic). Stem Cell Derived RPE for Treatment of Macular Degeneration

Anne McKechnie, RN, PhD. Extending an eHealth Enhanced Care Approach: Development of Nurse-Guided Patient Engagement Content to Support Human Milk Feeding for Infants with Complex Congenital Heart Disease

Paulo Pianosi, MD, and, Rajesh Rajamani, PhD. Wearable Ambulatory Breathing Sensor (WABS)

Carolina Sandoval-Garcia, MDIn collaboration with Cerovations, LLC. Improving CSF Shunt Reliability with Dual Lumen Catheter for Redundancy

Jessica Simacek, PhD and Adele Dimian, PhD. Bridging barriers to intervention access: Caregiver-delivered communication intervention

Ronald Siegel, PhD and James Cloyd, PhD. Development of a Prodrug/Enzyme Nasal Spray for Rapid Delivery of Diazepam for Treatment of Seizure Emergencies

Jill Siegfried, PhD. Cellular Uptake Mechanism of Cyclic STAT3 Decoy

Andrew Wu, MD. A low-resource oxygen blender prototype for use in modified bubble CPAP circuits

Collaboration with Earl E. Bakken Medical Devices Center Innovation Fellows Program. Project: Cleft palate closure device


Samuel Asirvatham, MD (Mayo Clinic). Epicardial pacing and defibrillation with a novel percutaneously implanted transverse sinus device

Jon Hawkinson, PhD. Critical path studies to nominate BINTA as a preclinical development candidate to treat chronic pain devoid of opioid side effect liability

John Ferguson, PhD, and Bernadette Gillick, PhD. Development of interactive software for use in pediatric stroke rehabilitation

Nicholas LaRusso, MD and Tatyana Masyuk, PhD (Mayo Clinic). In vitro and in vivo testing the effects of SBI 319, a novel TGR5 antagonist, in treatment of the cholangiopathies

Roy Cho, MD, MHA. Multi-compartment syringe for endobronchial ultrasound transbronchial needle aspiration

Collaboration with Earl E. Bakken Medical Devices Center Innovation Fellows Program. Qp:Qs monitor for single ventricle post-surgical monitoring


Matthew Ambrose, MDIn collaboration with Children’s Heartlink and One Heart Health. A telemedicine solution for congenital heart disease screening in low resource settings.

Hannah Bearinger, PhDChristie Traczyk, MSCourtney Hill, MD. Optimizing infant nutrition through breastmilk device.

Andreas Beutler, MD (Mayo Clinic) and James Collins, DVM, PhD. Intraganglionic Treatment for Chronic Locoregional Pain

Maneesh Bhargava, MD, PhD. Molecular Phenotyping in Acute Respiratory Distress Syndrome

Adam Choe, MSCourtney Hill, MDChristie Traczyk, MS. Dental fear and anxiety.

Arthur Erdman, PhD, and Courtney Hill, MD. Optimizing Infant Nutrition with Breastmilk Device

Juergen Konczak, PhD. Wearable non-invasive neuromodulation technology for the symptomatic treatment of the voice disorder spasmodic dysphonia

D. Dean Potter, MD, Dennis Wigle MD, PhD, and Stephanie Polites, MD (Mayo Clinic). Development of a Neonatal Esophageal Lengthening and Anastomotic Device

Tina Slusher, MDIfelayo Ojo, MBBS, MPHIn collaboration with Maternova, Inc. Liquid crystal display thermometer (LCDT) for measurement of infant body temperatures in low-resource care settings

Robert Tranquillo, PhD. Gap analysis for a pre-IND of a pediatric conduit with growth potential

Martin Zielinski, MD, and Jonathan M. Aho, MD (Mayo Clinic). Treatment of Tension Pneumothorax Decompression with Needle Thoracostomy Colorimetric Capnography

Collaboration with Earl E. Bakken Medical Devices Center Innovation Fellows Program:
Blood-pressure monitoring cuff to accurately capture blood pressure data in pediatric patients;
Wearable device for eczema to provide improved options for home-based treatment;
Seizure monitoring device for care takers to detect non tonic clonic seizures in children


Gregory J. Beilman, MD. Preclinical Development of Beta-hydroxybutyrate/Melatonin (BHB/M) for the Treatment of Trauma-induced Acute Blood Loss

Jeffrey Bishop, PharmD, MS. Pilot study of inflammatory markers and neurocognitive phenotypes in psychosis

Mikael Elias, PhD. A new technology to control microbes and increase the effectiveness of GI endoscope disinfection procedures

Amy Esler, PhD, and Rebekah L. Hudock, PhD. Development of a Visual Sequence Application for Children with Special Communication Needs

Naomi Fujioka, MD. Analysis of the health effect of kava as a dietary supplement

Gary Goldish, MD. Development of an arm cycle ergometer for supine use

Daniel Knights, PhD. Immigrant Microbiome Project

Aaron LeBeau, PhD. Imaging PD-L1 Expression in Drug-Resistant Prostate Cancer Models Using a Novel Human Antibody Contruct

Ling Li, PhD. Pharmacokintecis of Minnelide/Triptolide in the Brain

Grace Lin, MD, and Paul Friedman, MD (Mayo Clinic). Ambulatory Noninvasive Measurement of Potassium in Patients with Cardiac and Renal Disease to Prevent Rehospitalization

Wei Shen, PhD. Dissolvable Lacrimal Stents Using PLLA-P(βMδVL)-PLLA Degradable Bioelastomers

George Wilcox, PhD; Daniel Bruce, PhD; Philip Portoghese, PhD; Carolyn Fairbanks, PhD. Peripherally restricted combination therapy for inflammatory or cancer-related chronic pain

Collaboration with Earl E. Bakken Medical Devices Center Innovation Fellows Program. Dental anxiety


Samuel Asirvatham, MD and David R. Holmes, Jr., MD (Mayo Clinic). Combination Radiofrequency and Electroporation Energy for Balloon-Based Ablation and Drug Delivery: A Novel Treatment Modality for Atrial Fibrillation

Barry Borlaug, MD (Mayo Clinic). Minimally Invasive Pericardial Resection to Treat Heart Failure

Kenneth Beckman, PhD, and Daryl Gohl, PhD. Micrometer: Next-generation Standards for Microbiome Analysis

Michael Farrar, PhD. B Cell Transcription factors in Leukemia

Gwenyth Fischer, MD. Epinephrine Drug-delivery Device for use in Pediatric Cardiac Arrest

Sven-Ulrik Gorr, PhD. A Novel Antimicrobial Peptide for Drug-resistant Bacterial Infections

Kathleen A. Harder, PhD, and Ognjen Gajic, MD, MS (Mayo Clinic). Pilot Implementation of Cloud-based Electronic Checklist to Improve Daily ICU Rounds in Rural Access Hospitals

Steven Koester, PhD, and Bruce Gerbi, PhD. Development of Ultrasmall Wireless Radiation Sensors for In Vivo dosimetry in Cancer Therapy

Timothy Lander, MD and Robyroy MacIver, MD (Children’s Hospital MN), (previous PI: Filippo Coletti, PhD). Development of intraluminal bronchial stent utilizing patient specific anatomy for the pediatric population

Amber Lockridge. The Use of D-serine as a Novel Insulin Secretagogue and Oral Antidiabetic

Jamie Lohr, MDIn collaboration with The Newborn Foundation. Whoosh: Point of care pediatric heart imaging project

Silvia Mangia, PhD. Metabolic changes in the activated human visual cortex during mild hypoxia

David Morris, MD (Mayo Clinic). Fiber-optic Tube Thoracostomy Trocar for Improved Patient Chest Drainage

Valerie Pierre, PhD, and Robin Patel, MD (Mayo Clinic). Novel Biotechnology for Rapid, Point-of-Care Diagnosis of Bacterial Infection

David Potter, MD and Robert Schumacher, PhD. Development of Hexyl-Benzyl-Biguanide for Breast Cancer Therapeutics

Amy Skubitz, PhD.  Development of a Biomarker PRofile for Ovarian Cancer using Proseek Multiplex plates

Tina Slusher, MD and Ashley Bjorklund, MD. Advancement of modified bubble CPAP for use in children in low resource settings: a study of safety



Conrado Aparicio, PhD. GL13K Antimicrobial Peptide Coatings with Strong Resistance to Degradation and Sustained Activity for Preventing Dental Peri-implant Infection

Shai Ashkenazi, PhD. Depth-resolved Tissue Oxygen Needle Sensor

Anannaya Banga, PhD. SOX 9 positive cells of the bile duct - a promising target for making immune tolerant Beta cells for the cure of type 1 diabetes

Gregory Beilman, MD. Beta-hydroxybutyrate/melatonin (BHB/M) for the Treatment of Trauma-induced Acute Blood Loss

Lisa Coles, MS, PhD. Evaluation of Oral N-acetylcysteine Pharmacokinetics and Pharmacodynamics

Lester Drewes, PhD. Development of Novel Drugs for High Risk Triple Negative Breast Cancer Treatment

Arthur Erdman, PhD. Acoustic Modulation of the Phrenic Nerve for Treatment of Ventilator Induced Diaphragmatic Dysfunction

Benjamin Hackel, PhD. Molecular PET Imaging of MET with Small Protein Ligands

Hiroshi Hiasa, PhD. Toxicology and efficacy studies for the development of novel fluoroquinolones with anticancer activity

Allison Hubel, PhD. Project tile: High-throughput screening of multicomponent preservation solutions for mesenchymal stem cells

Paul Iaizzo, PhD. Neuromuscular blockade assessment of motor point stimulation

Alexander Khoruts, MD. Development of Immunoregulatory Microbiota to Suppress Gut Inflammation

Danni Li, PhD. Validation of Circulating Hyaluronan and Tumor-associated Hyaluronan Receptors as Prognostic Biomarkers in Prostate Cancer

Jayanth Panyam, PhD. A Novel Marker for Isolation and Characterization of Circulating Tumor Cells from Patients with Metastatic Cancer

Jayanth Panyam, PhD. Antibody Targeting Metastases in triple Negative Breast Cancer

David W. Polly, Jr., MD, and Charles Ledonio, MD. 3D rendering of the thoracic cage from plain 2D radiographs of scoliosis in children

David Potter, MD, PhD. Epoxygenase mechanisms of breast cancer progression

Kari Roberts, MD (previous PI, Arif Somani, MD). In collaboration with Abbe Vision, Inc. Intra-pulmonary aerosol generator for drug delivery in intubated patients

Michael Rosenberg, MD. Predicting rupture of abdominal aortic aneurysm (AAA) by anatomic and hemodynamic markers from in-vivo and in-vitro imaging

Elizabeth Seaquist, MD. Wearable Food Intake Tracking Device

Srinand Sreevatsan, PhD. Point-of-care Detection and Monitoring System for Tuberculosis

Robert Tranquillo, PhD. Preclinical demonstration of growth capacity of a tissue-engineered RVOT graft

David Walk, MD. Longitudinal MRI Spectroscopy in ALS


Gregor Adriany, PhD. A high density coil array for visual, auditory and motor cortex fMRI at 7 Tesla

Karen Ashe, MD, PhD. Project title: Rapid analysis of pathogenic tau proteins in human fluid specimens

Maneesh Bhargava, MD, PhD. SWIFT-MRI in Acute Respiratory Distress Syndrome

John Bischof, PhD. Improved Disease Diagnosis Using Lateral Flow Assays with Thermal Contrast

Wade Bresnahan, PhD. Identification of novel therapeutic targets against human cytomegalovirus using a genome wide shRNA screen and next generation sequencing

Michael Farrar, PhD. T Cell Epitope Discovery for Cancer Immunotherapy

Michael Farrar, PhD. Genomic analysis of BCR-ABL+ human leukemia with high versus low STAT5 activation

Deborah Ferrington, PhD. Enhancing Mitochondrial Function as a Treatment for Age-Related Macular Degeneration

Dan, Gallaher, PhD. The effect of viscous and fermentable dietary fiber consumption on the gut microbiota and its significance in obesity

Allison Hubel, PhD. Microfluidic Device for Removal of DMSO from Frozen and Thawed Cell Therapy Products

Hubert Lim, PhD. A New Noninvasive Approach for Brain Activation to Treat Tinnitus

Paula Ludewig, PhD, PT. Shoulder Motion Guided Patient Diagnostic and Treatment Classification

Theoden Netoff, PhD. Closed loop neuromodulation of seizures in an in vivo model of epilepsy

Mark Osborn, PhD. Engineered nuclease mediated generation of non-alloreactive, tumor specific T-cells for human cancer therapy

Julie Ostrander, PhD. Identification of PELP1 inhibitors

Jayanth Panyam, PhD. Development of tylocrebrine for clinical use as an anticancer agent

Jayanth Panyam, PhD. Surface Functionalized Nanoparticles for Improved Chemotherapeutic Efficacy

Jayanth Panyam, PhD. Silicate Prodrug Nanoparticles of Paclitaxel

Valerie Pierre, PhD. Iron-based fluorine MRI contrast agents

Wynne Schiffer, PhD. Simultaneous FDG PET and fMRI measures of functional connectivity in the rodent brain

Timothy Starr, PhD. Modeling combination targeted therapy

Alena Talkachova, PhD. Vagal nerve stimulation and stem cell cardio-transplantation: a novel combination therapy for heart disease

Robert Tranquillo, PhD. Preclinical Evaluation of a Novel Tissue-engineered Heart Valve

Chun Wang, PhD. Semi-solid Polymer Delivery Systems for Immunotherapy against Melanoma


Khalil Ahmed, PhD. Cancer Nanotherapeutic Targeting CK2

Michael Bowser, PhD. Tunable control of sarcoplasmic reticulum Ca2+ transport using single stranded DNA antagonists of a polyanion binding site on phospholamban

Scott Dehm, PhD. Genome engineering to model prostate cancer therapy resistance

Peter Dosa, PhD. Development of Novel Therapeutics for Glaucoma

Deborah Ferrington, PhD. Enhancing Mitochondrial Function as a Treatment for Age-Related Macular Degeneration

Erik Finger, MD, PhD. Isolation and Expansion of Regulatory T Cells from Patients with End Stage Liver Disease for the Induction of Tolerance in Transplantation

Melissa Geller, MD. Transposon-mediated targeting of natural killer cells for ovarian cancer immunotherapy

Jafar Golzarian, MD. Pharmacokinetic and Safety of Doxorubicin-Elutable Bioresorbable Microspheres in a Rabbit Model of Hepatic Arterial Embolization

Susanta Hui, MS, PhD. Advanced 3D MR imaging to characterize changes in the bone marrow of leukemia patients undergoing transplant

Marc Jenkins, PhD. Hepatitis B Conjugate Vaccine

Samir Khariwala, MD. SWIFT MRI for evaluation of mandibular invasion in oral squamous cell carcinoma

Michael Linden, MD, PhD. Identifying Immunophenotypic Markers Suitable for Clinical Laboratory Testing for Early Identification of Bortezomib Resistance in Human Multiple Myeloma

Steven Patterson, PhD, and Louis Mansky, PhD. Investigation of HIV-1 Lethal Mutagenesis in a Humanized HIV Mouse Model

Ann Parr, MD, PhD. Autologous OPCs for Transplantation into Human Spinal Cord Injury

Rita Perlingeiro, PhD. Therapeutic Approaches for Duchenne Muscular Dystrophy using iPS Cells

David Potter, MD, PhD. Epoxygenase Mechanisms of Breast Cancer Prevention

Valerie Pierre, PhD. Siderophore Aptasensors for Immediate Point-of-care Diagnosis of Urinary Tract Infection

Daniel Vallera, PhD. Developing Biological Drugs Targeting Chemo-Refractory Carcinoma

Carston R. Wagner, PhD. In vivo Proof-of-Concept Studies on Chemically Self Assembled Nanostructures (CSANS) as Targeted Diagnostic Imaging and Drug Delivery agents for Brain Cancer


Jodi Fenlon Rebuffoni
Assistant Director
[email protected]